Table 1. Characteristics of the Colaus sample.
| Overall (n = 6,184) | Male (n = 2,933) | Female (n = 3251) | |||||
| Mean | SD/IQR | Mean | SD/IQR | Mean | SD/IQR | p-value | |
| Age (years) | 53.1 | 10.8 | 52.6 | 10.8 | 53.5 | 10.7 | <0.001 |
| Alcohol consumption, % | 25.4 | 36.1 | 15.7 | <0.001 | |||
| Current smoking, % | 27 | 29.3 | 25 | <0.001 | |||
| Diabetes, % | 6.5 | 9.6 | 3.7 | <0.001 | |||
| Hypertension, % | 35.9 | 42.1 | 30.4 | <0.001 | |||
| Diuretics use, % | 2.3 | 1.7 | 2.8 | 0.003 | |||
| BMI (kg/m2) | 25.8 | 4.6 | 26.6 | 4 | 25.1 | 4.9 | <0.001 |
| Serum uric acid (µmol/L) | 313.5 | 84.5 | 361.1 | 75.7 | 270.6 | 67.2 | <0.001 |
| Fasting glucose (mmol/l) | 5.6 | 1.1 | 5.8 | 1.2 | 5.3 | 1 | <0.001 |
| GFR (ml/min/1.73 m2) | 83.6 | 16.6 | 86.7 | 17.4 | 80.7 | 15.2 | <0.001 |
| IL-1β (pg/mL)* | 0.4 | 0.1–1.7 | 1.5 | 0.7–3.5 | 1.2 | 0.5–2.9 | <0.001 |
| IL-6(pg/mL)* | 1.3 | 0.6–3.2 | 0.3 | 0.1–1.5 | 0.5 | 0.1–1.9 | <0.001 |
| TNF-α (pg/mL)* | 2.9 | 1.8–4.5 | 3 | 1.9–4.6 | 2.7 | 1.7–4.4 | <0.001 |
| CRP (mg/L)* | 1.3 | 0.6–2.7 | 1.2 | 0.6–2.6 | 1.3 | 0.6–2.9 | 0.013 |
BMI = body mass index; GFR = glomerular filtration rate (calculated according to Modification in Diet in Renal Disease equation); IL-1β = interleukin-1β; IL-6 = interleukin-6: TNF-α = tumour necrosis factor-alpha; CRP = ultrasensitive C-reactive protein.
Results are presented as mean (SD), percentages or median (interquartile range) for those marked with an asterix. Between-group comparisons by ttest, Chi-square test or Wilcoxon ranksum test.