Table 2. fMRI: factor main effects.
Region | Side | x | y | z | T-Score | kE (voxels) |
Main effect of familiarity: familiar>unfamiliar | ||||||
Precuneus | L | −9 | −54 | 30 | 7.76 | 3840 |
Anterior cingulate | L | −9 | 45 | 15 | 7.69 | # |
Inferior parietal lobule | R | 57 | −36 | 48 | 6.90 | # |
Right precuneus | R | 6 | −60 | 21 | 6.41 | # |
Anterior cingulate | L | −3 | 30 | 15 | 5.95 | # |
Anterior cingulate | R | 6 | 30 | 15 | 5.90 | # |
Inferior frontal gyrus | R | 48 | 6 | 18 | 5.93 | 325 |
Cerebellum | R | 60 | −57 | −9 | 5.09 | 195 |
Inferior temporal gyrus | R | 18 | −60 | −51 | 4.91 | 197 |
Postcentral gyrus | L | −39 | −45 | 63 | 4.83 | 439 |
Main effect of familiarity: unfamiliar>familiar | ||||||
Postcentral gyrus | R | 39 | −21 | 51 | 5.85 | 413 |
Precentral gyrus | R | 39 | −24 | 60 | 6.31 | # |
Rolandic operculum | R | 45 | −24 | 21 | 5.23 | 218 |
Main effect of group: control>aMCI-no suprathreshold clusters | ||||||
Main effect of group: aMCI>control-no suprathreshold clusters | ||||||
Main effect of stimulus type: faces>places | ||||||
Middle temporal gyrus | R | 57 | −63 | 9 | 9.97 | 1087 |
Supramarginal gyrus | R | 54 | −27 | 24 | 3.77 | # |
Angular gyrus | R | 57 | −57 | 36 | 3.69 | # |
Middle temporal gyrus | L | −54 | −57 | 12 | 6.15 | 569 |
Precuneus | 0 | −63 | 33 | 5.00 | 136 | |
Temporal pole | R | 30 | 9 | −24 | 4.63 | 130 |
Main effect of stimulus type: places>faces | ||||||
Fusiform gyrus | L | −27 | −45 | −15 | 19.66 | 9651 |
Middle occipital gyrus | L | −36 | −87 | 21 | 17.46 | # |
Middle occipital gyrus | R | 36 | 84 | 21 | 17.22 | # |
Fusiform gyrus | R | 30 | −39 | −15 | 16.49 | # |
Lingual gyrus | R | 18 | −75 | −6 | 14.20 | # |
Precentral gyrus | R | 30 | −3 | 51 | 5.10 | 159 |
Superior frontal gyrus | R | 30 | 15 | 63 | 3.72 | # |
All activations are significant at p<0.05, corrected for multiple comparisons at the cluster level (with a height threshold of p<0.001, uncorrected at the voxel level). For each region of activation, the coordinates of the maximally activated voxels within the activation cluster are given in standard stereotactic MNI space. # indicates that this activation maximum is part of the same cluster.