. 2011 May 20;6(5):e20336. doi: 10.1371/journal.pone.0020336

Table 1. Metabolite concentrations in the in vivo mouse brain measured with ¹H-MRS over a 223 mm³ and 31.22.8 mm³ volume of interest in the thalamic region and the prefrontal cortex, respectively.

	Thalamus							Prefrontal Cortex
	Control mouse[mM/l] ± %SD			Aspa-LacZ[mM/l] ± %SD			Change%	Control mouse[mM/l] ± %SD			Aspa-LacZ[mM/l] ± %SD			Change%
GABA	3.84	±	4	2.63	±	10	−31.4%	2.65	±	7	1.95	±	22	−26.4%
Glc	6.19	±	6	4.63	±	12	−25.2%	7.19	±	5	N/A	±	N/A	N/A
Tau	5.50	±	3	16.75	±	2	204.4%	11.53	±	2	14.12	±	3	22.4%
Gln	3.65	±	4	8.12	±	3	122.2%	2.36	±	6	2.38	±	14	0.7%
Glu	9.28	±	2	3.06	±	9	−67.0%	11.21	±	2	8.25	±	5	−26.4%
mI	8.06	±	2	34.70	±	1	330.6%	6.59	±	3	11.56	±	5	75.4%
Lac	5.08	±	4	2.55	±	12	−49.9%	3.90	±	6	3.48	±	16	−10.9%
Ch	2.58	±	2	1.30	±	4	−49.5%	2.35	±	2	2.59	±	5	10.4%
NAA	11.56	±	2	41.13	±	1	255.8%	11.21	±	2	19.68	±	3	75.5%
Cr	9.66	±	1	10.75	±	2	11.4%	9.50	±	2	9.50	±	4	0.0%

The standard deviation of the metabolite concentrations (SD) corresponds to the Cramér-Rao lower bounds of the LCModel-fit and is given in %. SD-values below 20% are considered reliable. Error bars are derived through the fit-routine and indicate the quality of individual metabolite measurements. Cr: Creatine and Phosphocreatine, NAA: NAA+NAAG, Cho: Phosphocholine and Glycerophosphorylcholine, Glu: Glutamate, Gln: Glutamine, mI: Myo-Inositol, Tau: Taurine, Glc: Glucose.

Table 1. Metabolite concentrations in the in vivo mouse brain measured with 1H-MRS over a 2*2*3 mm3 and 3*1.2*2.8 mm3 volume of interest in the thalamic region and the prefrontal cortex, respectively.

Table 1. Metabolite concentrations in the in vivo mouse brain measured with ¹H-MRS over a 223 mm³ and 31.22.8 mm³ volume of interest in the thalamic region and the prefrontal cortex, respectively.