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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Semin Arthritis Rheum. 2010 Nov 2;40(6):512–531.e8. doi: 10.1016/j.semarthrit.2010.07.009

Figure 2. Funnel plot of the risk estimates (odds ratios or relative risks) of developing autoimmune disease associated with vitamin D intake (none vs. supplementation or highest vs. lowest level of intake).

Figure 2

Sample size of the study refers to the number of autoimmune disease cases in each study. The appearance of an inverted funnel, where small studies of positive and negative studies have been published argues against a potential publication bias.