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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: J Immunol. 2011 Apr 27;186(11):6597–6606. doi: 10.4049/jimmunol.1004074

FIGURE 2.

FIGURE 2

Addition of Stat4 deficiency prevents colitis by Stat6/T-bet DKO cells. A, Relative body weight of SCID mice after transfer of 4 × 105 wildtype, DKO, or TKO CD4+CD25−CD45RBhigh cells. H&E staining (B) and fluorescent immunohistochemistry (C) for CD4, CD11c, and CD68 in the distal colons of SCID mice 8 or 12 wk after T cell reconstitution (original magnification ×100). Representative sections are shown from 10 mice in each group. Histological scoring of colitis was described in Materials and Methods.