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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: J Immunol. 2011 Apr 27;186(11):6597–6606. doi: 10.4049/jimmunol.1004074

FIGURE 5.

FIGURE 5

Stat4 deficiency results in higher levels of Foxp3+ Tregs. A, Immunohistochemistry for CD4 and Foxp3 in the distal colons and MLN in SCID mice 8 wk after T cell reconstitution (original magnification ×200). Representative sections are shown from 10 mice in each group. B, Intracellular staining for Foxp3 on gated MLN CD4 cells 8 wk after adoptive transfer (upper panels) and real-time RT-PCR for Foxp3 expression on MLN CD4 T cells 2 or 8 wk after adoptive transfer (lower panel). **p < 0.01.