Figure 5. Effect of C48 on Stat3 nuclear translocation.
Effect of C48 on Oncostatin M (OSM)-induced activation and nuclear localization of Stat3-YFP protein (yellow) in serum-starved, MEF-Stat3-YFP expressing cells. The nuclei (blue) are stained with DAPI. Not all cells are transfected with the Stat3-YFP construct. Upper panel: 100x, lower panel 10x magnification. One representative result from 2 independent experiments is shown.