Table 1.
Percentage of Beating Grafts at 2 Weeks After In Vivo Implantation
| |
Beating grade at 2 weeks after implant |
||
|---|---|---|---|
| Atrial patch treatment groups | 0+ | 1+ | 2+ |
| Precultured with CoPP (high level HO-1 induction) | 27% (4/15) | 27% (4/15) | 47% (7/15)a |
| Precultured without CoPP (low level HO-1 induction) | 44% (7/16) | 50% (8/16) | 6% (1/16)a |
| Implanted without culture or CoPP (no HO-1 induction at implantation) | 56% (9/16) | 44% (7/16) | 0% (0/16)a |
| Precultured with CoPP+SnPP | 86% (6/7) | 14% (1/7) | 0% (0/7) |
| Precultured with SnPP alone | 86% (6/7) | 14% (1/7) | 0% (0/7) |
a
p<0.03, Differences between treatment groups, Kruskal–Wallis.
Beating grades are compared between groups under different treatment conditions.
HO-1, heme oxygenase-1; CoPP, cobalt protoporphyrin, an inducer of HO-1; SnPP, tin protoporphyrin, a specific inhibitor of HO-1 activity.