. 2011 Mar 3;21(2):102–118. doi: 10.1007/s11065-011-9163-0

Table 4.

Correlations between brain abnormalities and measures of alcohol exposure or facial dysmorphology

First author, year	Subjects	Findings
Astley et al. 2009	30 FAS/pFAS, 30 SE:AE	# Drinking days/week—midsagittal area, hippocampal volume, length of corpus callosum
Astley et al. 2009	30 FAS/pFAS, 30 SE:AE	Max # drinks/occasion—frontal lobe volume, caudate volume, hippocampal volume
Cortese et al. 2006	10 exposed (7 FAS), 4 HC	Amount of alcohol consumed at conception—caudate volume
Roussotte et al. 2011	17 exposed	# drinks/week in 1st trimester—intracranial volume
Facial Dysmorphology
Astley et al. 2009	30 FAS/pFAS, 30 SE:AE	FAS/pFAS group had smaller area/volume than SE:AE group for: midsagittal brain and cerebellar area, frontal lobe total and gray matter volume, putamen volume
Roussotte et al. 2011	52 exposed	Palpebral fissure length—ventral diencephalon volume
Roussotte et al. 2011	52 exposed	Lipometer—thalamus and left pallidum volume