Table 5.
Baroreflex parameters for LSNA (as % of CON) and HR (in bpm) after microinjection of insulin (0.6, 6 and 60 nU) or aCSF into the PVN
| CON (n = 4) | 0.6 nU | 6 nU | 60 nU | CON (n = 6) | aCSF | |
|---|---|---|---|---|---|---|
| LSNA | ||||||
| Max (% control) | 209 ± 49 | 209 ± 45 | 210 ± 52 | 188 ± 58 | 155 ± 28 | 154 ± 40 |
| Min (% control) | 9 ± 4 | 5 ± 5 | 9 ± 4 | 4 ± 4 | 29 ± 9 | 46 ± 19 |
| Range (% control) | 200 ± 44 | 204 ± 49 | 201 ± 51 | 186 ± 56 | 126 ± 31 | 108 ± 21 |
| BP50 (mmHg) | 103 ± 8 | 100 ± 6 | 96 ± 7 | 88 ± 13 | 100 ± 3 | 104 ± 6 |
| Width (mmHg) | 11 ± 2 | 11 ± 1 | 11 ± 1 | 14 ± 2 | 15 ± 3 | 14 ± 3 |
| HR | ||||||
| Max (bpm) | 398 ± 20 | 402 ± 26 | 395 ± 24 | 378 ± 34 | 459 ± 23 | 459 ± 34 |
| Min (bpm) | 304 ± 13 | 310 ± 11 | 310 ± 6 | 308 ± 12 | 344 ± 13 | 360 ± 5 |
| Range (bpm) | 93 ± 13 | 92 ± 18 | 85 ± 22 | 70 ± 21 | 114 ± 13 | 99 ± 30 |
| BP50 (mmHg) | 129 ± 8 | 132 ± 3 | 122 ± 10 | 123 ± 3 | 124 ± 3 | 127 ± 1 |
| Width (mmHg) | 14 ± 2 | 13 ± 3 | 12 ± 2 | 10 ± 1 | 14 ± 1 | 8 ± 1 |