Table 9.
Baroreflex parameters for LSNA (as % of CON) and HR (in bpm) after microinjection of insulin (0.6, 6 and 60 nU) or aCSF into the ArcN
| CON (n = 6) | 0.6 nU | 6 nU | 60 nU | CON (n = 8) | aCSF | |
|---|---|---|---|---|---|---|
| LSNA | ||||||
| Max (% control) | 238 ± 57 | 374 ± 73* | 401 ± 101* | 412 ± 86* | 163 ± 12 | 190 ± 12 |
| Min (% control) | 11 ± 8 | 13 ± 9 | 6 ± 12 | 10 ± 10 | 8 ± 9 | 21 ± 12 |
| Range (% control) | 226 ± 62 | 361 ± 75* | 395 ± 104* | 406 ± 84* | 156 ± 14 | 168 ± 12 |
| BP50 (mmHg) | 99 ± 3 | 103 ± 2 | 104 ± 3 | 103 ± 5 | 103 ± 6 | 94 ± 4 |
| Width (mmHg) | 14 ± 1 | 13 ± 1 | 12 ± 1 | 13 ± 1 | 14 ± 2 | 11 ± 2 |
| HR | ||||||
| Max (bpm) | 428 ± 13 | 422 ± 11 | 426 ± 11 | 434 ± 13 | 429 ± 14 | 431 ± 12 |
| Min (bpm) | 293 ± 12 | 308 ± 7 | 314 ± 8 | 313 ± 10 | 311 ± 19 | 312 ± 8 |
| Range (bpm) | 135 ± 16 | 114 ± 12 | 112 ± 14 | 122 ± 18 | 118 ± 14 | 119 ± 16 |
| BP50 (mmHg) | 120 ± 4 | 124 ± 5 | 123 ± 6 | 124 ± 3 | 116 ± 5 | 111 ± 6 |
| Width (mmHg) | 10 ± 1 | 13 ± 1 | 12 ± 1 | 11 ± 1 | 12 ± 2 | 14 ± 1 |
*
P < 0.05 vs. CON.