Figure 10. Effect of carbenoxolone on the half-width of responses to exogenous GABAergic applications and of inhibitory postsynaptic potentials in interneurons from Cx36 KO animals.

A, left, summary graph comparing half-widths of voltage-clamp responses to GABA puffs in control and in the presence of carbenoxolone (cbx) for individual experiments (lines) and for their overall average (red circles). Traces in control, in the presence of carbenoxolone and superimposed are shown in the right panel. B, as in A, but data and analysis regards evoked inhibitory postsynaptic currents (IPSCs). Notice that carbenoxolone has a similar effect on GABA puffs and IPSCs. NBQX (20 μm), d-AP5 (50 μm) and CGP55845 (5 μm) present throughout in A and B.