Figure 2. ls/ls mice show normal visceromotor responses to bladder distension.

A, visceromotor responses in control mouse to graded bladder distensions (20–100 mmHg). B, similar responses were seen in ls/ls mice. C, averaged visceromotor responses did not differ significantly in controls and ls/ls mice. D and E, similar CGRP immunoreactivity from spinal afferents innervating the control and ls/ls mouse bladder detrusor muscle. F, no statistical difference was found in total density of CGRP immunoreactivity between the bladders of control and ls/ls mice when measured as a percentage of field of view.