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. 2011 Jan 31;589(Pt 7):1725–1740. doi: 10.1113/jphysiol.2010.202366

Figure 2. EphrinA1-Fc administration reduces infarct size, chamber dilatation, necrosis, and thinning of the left ventricular free wall.

Figure 2

Representative histological images shown are of IgG-Fc-treated (A) and ephrinA1-Fc-treated (B) hearts 4 days post-MI. There was a 50% reduction in infarct size (C), 64% less necrosis (D), 35% less chamber dilatation (E), and 32% less thinning of the left ventricular free wall (F) in ephrinA1-Fc-treated hearts compared to IgG-Fc-treated hearts. n = 7 control, n = 9 IgG-Fc, n = 9 ephrinA1-Fc. P < 0.05: †different from control; *different from IgG-Fc. LV, left ventricle; RV, right ventricle; N, necrosis; G, granulation tissue.