Table 1.
Laboratory data of the studied groups
| Variable | Overweight N=37 (mean ± SD) | Obese N=39 (mean ± SD) | P value | Total studied cases N=76 (mean ± SD) | Abnormal tests N (%) |
|---|---|---|---|---|---|
| Cortisol (μg/dl) | 1.5 ± 0.5 | 1.4 ± 0.6 | 0.6 | 1.5 ± 0.5 | 0 (0) |
| ACTH (pg/ml) | 5.3 ± 1 | 4.9 ± 1.1 | 0.1 | 5.1 ± 1.1 | 0 (0) |
| Fasting blood glucose (mg/dl) | 88.7 ± 8.2 | 89.7 ± 8.4 | 0.6 | 89.2 ± 8.3 | 9 (11.8) |
| Total cholesterol (mg/dl) | 170 ± 19.9 | 175.4 ± 22.4 | 0.3 | 172.8 ± 21.3 | 24 (31.6) |
| Triglyceride (mg/dl) | 112.7 ± 38.7 | 134.4 ± 52.3 | 0.05* | 124.1 ± 47.3 | 25 (32.9) |
| HDL-c (mg/dl) | 47.4 ± 9.8 | 41.8 ± 9.2 | 0.01* | 44.4 ± 9.8 | 10 (13.2) |
| LDL-c (mg/dl) | 79.1 ± 19.7 | 87.8 ± 17.9 | 0.02* | 83.7 ± 19.1 | 3 (3.9) |
| Insulin (µIU/ml) | 13.4 ± 4.7 | 15.2 ± 6.9 | 0.3 | 14.3 ± 6.0 | 23 (30.3) |
| C-peptide (ng/ml) | 1.4 ± 0.7 | 1.8 ± 0.8 | 0.03* | 1.6 ± 0.8 | 21 (27.6) |
| HOMA-IR | 3.1 ± 0.9 | 4.3 ± 0.8 | 0.0001* | 3.2 ± 1.4 | 21 (27.6) |
| Total serum bilirubin (mg/dl) | 0.5 ± 0.3 | 0.6 ± 0.2 | 0.2 | 0.5 ± 0.2 | 0 (0) |
| Direct serum bilirubin (mg/dl) | 0.4 ± 0.2 | 0.4 ± 0.1 | 0.7 | 0.4 ± 0.2 | 0 (0) |
| AST (IU/l) | 27.7 ± 15.2 | 30.5 ± 9 | 0.02* | 29.2 ± 12.3 | 6 (7.9) |
| ALT (IU/l) | |||||
| Median | 24 | 36.5 | 0.0001* | 31.1 ± 23.9 | 16 (21) |
| Min-max | 13-218 | 16-55 | |||
| AP (IU/l) | 297.9 ± 73.9 | 341.8 ± 64.6 | 0.006* | 321 ± 72.1 | 0 (0) |
| GGT (IU/l) | 28.6 ± 17.2 | 30.7 ± 10.9 | 0.1 | 29.7 ± 14.2 | 0 (0) |
| Serum albumin (g/dl) | 4.3 ± 0.2 | 4.3 ± 0.2 | 0.2 | 4.3 ± 0.2 | 0 (0) |
| PC(%) | 85.6 ± 5 | 88 ± 7.2 | 0.2 | 86.9 ± 6.4 | 0 (0) |
| Serum ferritin(μg/l) | 51.8 ± 21.1 | 61.8 ± 36.2 | 0.3 | 57.1 ± 30.3 | 0 (0) |
| Biopsy proven NAFLD (N=33) | 0 (0) | 15 (38.5) | <0.0001 | 33/76 | 15 (45.5) |
Figures in parenthesis are in percentage