Table 3.

Comparison of data of patients with normal liver histology, simple steatosis, and NASH

Variable	Normal histology (Mean ± SD) (n= 18)	Simple steatosis(Mean ± SD) (n= 8)	NASH (Mean ± SD) (n= 7)	P value
BMI	30.0 ± 2.2a	36.6 ± 4.3b	38.4 ± 6.4b	0.0001*
SSFT (cm)	25.1 ± 2.6a	34.3 ± 2.0b	31.6 ± 3.7b	0.0001*
W/H ratio	0.9 ± 0.03a	1.0 ± 0.08b	1.0 ± 0.2b	0.0001*
Total cholesterol (mg/dl)	170.2 ± 21.4a	191.4 ± 11.4b	194.1 ± 8.5b	0.004*
HDL-c (mg/dl)	44.1 ± 7.6a	36.9 ± 8.3b	33.6 ± 6.1b	0.007*
LDL-c (mg/dl)	78.6 ± 14.4a	100.0 ± 14.5b	104.9 ± 16.6b	0.0001*
Triglyceride (mg/dl)	124.9 ± 41.6a	170.8 ± 31.6b	195.9 ± 36b	0.001*
Insulin (μIU/ml)	12.4 ± 6.0a	20.2 ± 8.5b	19.6 ± 6.4b	0.02*
C-peptide (ng/ml)	1.4 ± 0.6a	2.3 ± 0.8b	2.7 ± 0.5b	0.0001*
HOMA-IR	3.1 ± 0.9a	4.3 ± 0.8b	4.1 ± 0.8b	0.0001*
Total bilirubin (mg/dl)	0.4 ± 0.1a	0.6 ± 0.1a	0.7 ± 0.2b	0.01*
Direct bilirubin (mg/dl)	0.3 ± 0.1a	0.4 ± 0.1a	0.4.1 ± 0.1b	0.02*
AST (U/l)	27.3 ± 9.2a	30.0 ± 8.5ab	37.6 ± 8.9b	0.04*
ALT (U/l)	28.6 ± 7.4a	40.8 ± 6.0b	44.6 ± 6.1b	0.0001*
AP (U/l)	319.4 ± 56.8a	370.5 ± 39.8b	404.1 ± 68.1b	0.004*
GGT	26.3 ± 8.0a	33.3 ± 10.5a	43.4 ± 8.3b	0.002*
Serum albumin (g/dl)	4.4 ± 0.2	4.4 ± 0.3	4.2 ± 0.3	0.3
PC (%) 85.6 ± 5.4	91.9 ± 8.4	90.7 ± 9.3	0.08
Serum ferritin (μg/l)	55.2 ± 21.9	88.4 ± 64	53.78 ± 19	0.5

P value is significant if < 0.05^*

Different symbols indicate signifi cant difference. Figures in parenthesis are in percentage