Table 3.

Relationship of various parameters with the presence or absence of large esophageal varices on univariate analysis

Variable	Small (Grade I-II) or no varices (n=148)	Large varices (Grade III-IV) (n=81)	P value
Male/ female	88/60	53/28	NS
Median age (range)	41 (17–73)	43 (17–67)
Ascites	83	49	NS
Splenomegaly	77	53	NS
Hepatic encephalopathy	19	24	NS
CTP class (A vs B/C)			0.001
Class A	38	4
Class B	89	38
Class C	21	39
Hemoglobin (g/dl)	9.2 (4.9–17.2)	9.8 (4.8–14.2)	NS
S albumin (g/dl)	3.0 (1.6–5.0)	2.7 (1.8–3.9)	NS
S bilirubin (mg/dl)	1.1 (0.4–14.6)	2 (0.8–10)	NS
Prothrombin time (seconds prolonged)	6 (0–20)	8 (0–28)	NS
Platelet count (per μl)	104500 (15000– 402000)	78000 (28000– 219000)	0.001
Spleen bipolar diameter (mm)	155 (70–300)	180 (85–290)	0.001
Portal vein diameter (mm)	13 (9–23)	14 (10–23)	0.005
Platelet count/ spleen diameter ratio	699.33 (115.38– 4466.67)	462.50 (96.55– 1078.81)	0.001