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. Author manuscript; available in PMC: 2012 May 13.
Published in final edited form as: Cell. 2011 May 5;145(4):622–634. doi: 10.1016/j.cell.2011.03.042

Figure 4. GRO-seq reveals the dynamics of E2-dependent transcription.

Figure 4

(A) Metagene representations showing the average profile of GRO-seq sequence reads near and at the TSSs of RefSeq genes in each of the four classes during the E2 treatment time course.

(B and C) Gene-specific views of the leading (B) and lagging (C) edges of a Pol II “wave” shown for the up-regulated gene JARID2 (B) and the down-regulated gene ESR1 (C), respectively, during the E2 treatment time course.

See also Figure S4.