Table 3.

EoE Diagnosis

	All Respondents (n= 72)	Academic GI (n= 34)	Community GI (n=38)	p-value *
Do you put biopsies from different locations in different pathology jars: (% yes)	65%	79%	53%	0.02
From where in the esophagus do you take biopsies:
Proximal + Middle + Distal (%)	44%	47%	42%	NS
Proximal + Distal (%)	33%	44%	24%	NS
Middle + Distal (%)	14%	6%	21%	NS
Proximal + Middle (%)	4%	3%	5%	NS
Middle only (%)	4%	0%	8%	NS
Do you require that a patient is on a PPI prior to making the diagnosis of EoE: (% yes)	31%	44%	18%	0.02
If yes, do you use once daily or twice daily dosing?
Once daily	45%	53%	29%	NS
Twice daily	55%	47%	71%	NS
If yes, what is the duration of treatment?
Range (weeks)	4 –12	4 –8	4 –12
Mean ± s.d.	6 ± 2	6 ± 2	6 ± 3	NS
Which of the following do you require to make the diagnosis of EoE:
Positive biopsy only	15%	9%	21%	NS
Consistent symptoms only	0%	0%	0%	NS
Consistent symptoms + Positive biopsy	19%	24%	16%	NS
Positive endoscopy findings + Positive biopsy	10%	3%	16%	NS
Consistent symptoms + Positive Biopsy + One of the following: No clinical response to a PPI, No histologic response to a PPI, and/or Negative pH testing**	13%	24%	3%	0.007
Consistent symptoms + Positive endoscopy findings + Positive biopsy + One of the following: No clinical response to a PPI, No histologic response to a PPI, and/or Negative pH testing	15%	15%	16%	NS
Consistent symptoms + Positive endoscopy findings + Positive biopsy	26%	27%	26%	NS

EoE, eosinophilic esophagitis; GI, gastroenterologist; NS, not significant

^*Comparison between academic and community GI performed with 2 sample t-test, Pearson’s chi-square test or Fisher’s Exact Test

^**EoE Consensus Guidelines