Table 4.

EoE Medical Treatment

	All Respondents (n= 72)	Academic GI (n= 34)	Community GI (n=38)	p-value *
What is your first line of therapy for treating EoE:
Proton pump inhibitor once daily	14%	9%	19%	NS
Proton pump inhibitor twice daily	17%	24%	11%	NS
Swallowed topical steroid from an inhaler (ie fluticasone)	54%	53%	56%	NS
Swallowed topical steroid in liquid form (ie budensonide)	0%	0%	0%	NS
Swallowed topical steroid in a thickened liquid form (ie budesonide slurry)	3%	3%	3%	NS
Systemic steroid (ie prednisone)	0%	0%	0%	NS
Empiric dietary elimination therapy	1%	3%	0%	NS
Targeted dietary elimination therapy based on allergy testing	3%	3%	3%	NS
Elemental diet	0%	0%	0%	NS
Leukotriene antagonist (ie montelukast)	3%	0%	6%	NS
Immunomodulator (ie 6MP or azathioprine)	0%	0%	0%	NS
Biologic (ie infliximab or mepolizumab)	0%	0%	0%	NS
Other	4%	6%	3%	NS
	All Respondents (n= 41)	Academic GI (n= 19)	Community GI (n=22)	p-value *
Of gastroenterologists who prescribe swallowed steroid first line, what is your second line therapy for EoE in patients who do not respond to initial therapy:
Proton pump inhibitor once daily	5%	5%	5%	NS
Proton pump inhibitor twice daily	5%	5%	5%	NS
Swallowed topical steroid from an inhaler (ie fluticasone)	5%	0%	9%	NS
Swallowed topical steroid in liquid form (ie budensonide)	10%	11%	9%	NS
Swallowed topical steroid in a thickened liquid form (ie budesonide slurry)	12%	16%	9%	NS
Systemic steroid (ie prednisone)	29%	32%	27%	NS
Empiric dietary elimination therapy	7%	11%	5%	NS
Targeted dietary elimination therapy based on allergy testing	17%	16%	18%	NS
Elemental diet	2%	5%	0%	NS
Leukotriene antagonist (ie montelukast)	7%	0%	13%	NS
Immunomodulator (ie 6MP or azathioprine)	0%	0%	0%	NS
Biologic (ie infliximab or mepolizumab)	0%	0%	0%	NS
Other	0%	0%	0%	NS

EoE, eosinophilic esophagitis; GI, gastroenterologist; NS, not significant

^*Comparison between academic and community GI performed Pearson’s chi-square test or Fisher’s Exact Test