Figure 2.
Experimental results showing that a SINE allows for safe delivery of DC to nerve. a) Typical results comparing DC delivery using a traditional platinum cuff electrode and a SINE. Abscissa is experiment time, and ordinate is proximally elicited muscle force normalized to distally elicited muscle force. Long-term (2–4 hour) recovery for the platinum electrode experiments is overlaid on the plot. (b-c) Data suggesting that DC-induced suppression using the SINE is a reversible phenomenon. b) The amount of DC required to induce prolonged suppression decreases asymptotically with cumulative DC, and rebounds after a 30 minute rest period. c) The time for recovery of conduction after DC-induced prolonged suppression increases asymptotically with cumulative DC delivery and rebounds after a 30 minute rest period.