Figure 2.
(A) Two-dimensional hierarchical cluster analysis of AIP and non-AIP CP demonstrating a clear separation between the two varieties. Blue color refers to downregulation in AIP and red color to upregulation. Clustering of patients was based on 358 differentially-regulated genes (for details see methods).
(B) Graph indicating functional relationships between differentially-regulated genes based on Gene Ontology annotations. Threshold is a GO depth of ≥8. Only the 79 genes that reached or exceeded the threshold are shown. Nodes represent genes and are labeled with the HUGO symbol. Edges show the connection between the two nodes that are compared. 26 different biological processes based on Gene Ontology terms are represented.