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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Am J Gastroenterol. 2010 Apr 20;105(9):2060–2071. doi: 10.1038/ajg.2010.141

Figure 3.

Figure 3

Figure 3

Figure 3

Proteome analysis

(A) Representative, silver-stained 2D gel electrophoresis gels of human pancreas (pH 4–7). The regions with major spot intensity changes are indicated: 1: anionic trypsinogen (PRSS2); 2: (pro)elastase 3B (ELA3B) & mesotrypsinogen (PRSS3); 3: cationic trypsinogen (PRSS1); 4: regenerating protein I.

(B) Protein levels in the tissue of AIP patients, ACP patients and healthy controls. The boxes indicate the median/mean and 25th/75th percentiles.

(C) Overlaid DIGE gel of murine pancreas; green channel: MAIDS infected mouse; red channel: healthy mouse. The spot regions with differentially-regulated proteases are indicated: 1: trypsinogen-20; 2: chymotrypsinogen B and trypsinogen-8; 3: (pro)elastase 3B.