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. Author manuscript; available in PMC: 2011 May 23.
Published in final edited form as: Cochrane Database Syst Rev. 2009 Jan 21;(1):CD007587. doi: 10.1002/14651858.CD007587

Comparison 2.

Acupuncture vs. sham interventions

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Response 5 Risk Ratio (M-H, Random, 95% CI) Subtotals only
 1.1 Up to 8 weeks/2 months after randomization 4 723 Risk Ratio (M-H, Random, 95% CI) 1.24 [1.02, 1.50]
 1.2 3 to 4 months after randomization 4 703 Risk Ratio (M-H, Random, 95% CI) 1.24 [1.05, 1.46]
 1.3 5 to 6 months after randomization 4 723 Risk Ratio (M-H, Random, 95% CI) 1.18 [1.02, 1.37]
 1.4 > 6 months after randomization 1 30 Risk Ratio (M-H, Random, 95% CI) 1.5 [0.53, 4.26]
2 Number of headache days 5 Mean Difference (IV, Random, 95% CI) Subtotals only
 2.1 Up to 8 weeks/2 months after randomization 4 682 Mean Difference (IV, Random, 95% CI) −1.56 [−3.02, −0.10]
 2.2 3 to 4 months after randomization 4 653 Mean Difference (IV, Random, 95% CI) −1.94 [−3.15, −0.72]
 2.3 5 to 6 months after randomization 4 670 Mean Difference (IV, Random, 95% CI) −1.57 [−2.97, −0.17]
 2.4 > 6 months after randomisation 0 0 Mean Difference (IV, Random, 95% CI) Not estimable
3 Headache intensity 4 Std. Mean Difference (IV, Random, 95% CI) Subtotals only
 3.1 Up to 8 weeks/2 months after randomization 2 111 Std. Mean Difference (IV, Random, 95% CI) −0.16 [−0.53, 0.21]
 3.2 3 to 4 months after randomization 3 623 Std. Mean Difference (IV, Random, 95% CI) −0.12 [−0.28, 0.04]
 3.3 5 to 6 months after randomization 4 670 Std. Mean Difference (IV, Random, 95% CI) −0.20 [−0.35, −0.04]
 3.4 > 6 months after randomisation 0 0 Std. Mean Difference (IV, Random, 95% CI) Not estimable
4 Analgesic use 3 Std. Mean Difference (IV, Random, 95% CI) Subtotals only
 4.1 Up to 8 weeks/2 months after randomization 3 266 Std. Mean Difference (IV, Random, 95% CI) −0.31 [−0.56, −0.06]
 4.2 3 to 4 months after randomization 3 261 Std. Mean Difference (IV, Random, 95% CI) −0.30 [−0.56, −0.05]
 4.3 5 to 6 months after randomization 1 167 Std. Mean Difference (IV, Random, 95% CI) −0.16 [−0.48, 0.17]
 4.4 > 6 months after randomisation 1 30 Std. Mean Difference (IV, Random, 95% CI) −0.33 [−1.06, 0.39]
5 Headache score 2 Std. Mean Difference (IV, Random, 95% CI) Subtotals only
 5.1 Up to 8 weeks/2 months after randomization 2 206 Std. Mean Difference (IV, Random, 95% CI) −0.03 [−0.31, 0.26]
 5.2 3 to 4 months after randomization 2 205 Std. Mean Difference (IV, Random, 95% CI) −0.11 [−0.40, 0.18]
 5.3 5 to 6 months after randomization 1 167 Std. Mean Difference (IV, Random, 95% CI) −0.06 [−0.38, 0.26]
 5.4 > 6 months after randomisation 1 30 Std. Mean Difference (IV, Random, 95% CI) −0.17 [−0.89, 0.54]