Table 6.
Incidence of Infusion Reactions by Study Site
| Gastroenterology site | Number of patients, n | Number of infusions, n | Pretreated first infusions, n (%) | Pretreated any infusions, n (%) | Infusion reactions at first infusion, n (%) | Infusion reactions at any infusion, n (%) | Patients on immunosuppressives, n (%) | Most common pretreatment protocol* |
|---|---|---|---|---|---|---|---|---|
| 1 | 60 | 934 | 8 (13.3) | 92 (9.9) | 0 | 13 (1.4) | 44 (73.3) | 4 |
| 2 | 37 | 589 | 31 (83.8) | 578 (98.1) | 2 (5.4) | 9 (1.5) | 22 (59.5) | 1 |
| 3 | 50 | 1,017 | 3 (6.0) | 674 (66.3) | 3 (6.0) | 52 (5.1) | 31 (62.0) | 2 |
| 4 | 34 | 581 | 30 (88.2) | 494 (85.0) | 0 | 2 (0.3) | 26 (76.5) | 2 |
| 5 | 44 | 543 | 44 (100.0) | 543 (100.0) | 0 | 3 (0.6) | 38 (86.4) | 1 |
| 6 | 64 | 701 | 63 (98.4) | 689 (98.3) | 2 (3.1) | 40 (5.7) | 38 (59.4) | 3 |
| 7 | 45 | 434 | 3 (6.7) | 97 (22.4) | 0 | 19 (4.4) | 40 (88.9) | 4 |
| 8 | 60 | 865 | 1 (1.7) | 235 (27.2) | 4 (6.7) | 67 (7.7) | 41 (68.3) | 4 |
| 9 | 42 | 600 | 2 (4.8) | 134 (22.3) | 4 (9.5) | 18 (3.0) | 32 (76.2) | 5 |
| Other sites | 11 | 204 | 5 (45.5) | 88 (43.1) | 0 | 3 (1.5) | 10 (90.9) | NA |
| Total | 447 | 6,468t | 190 (42.5) | 3,624 (56.0) | 15 (3.4) | 226 (3.5) | 322 (72.0) | NA |
*
Most common pretreatment protocol used at each site: 1: acetaminophen, nonsedating antihistamine; 2: acetaminophen, standard antihistamine; 3: acetaminophen, standard antihistamine, H2-antagonist; 4: acetaminophen, standard antihistamine, corticosteroid; 5: acetaminophen; NA= not applicable.
†
One infusion had unknown infusion reaction status.