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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2011 Feb 24;252(3):211–220. doi: 10.1016/j.taap.2011.02.005

Figure 3. Time course of APAP toxicity.

Figure 3

B6C3F1 mice were treated with APAP (200 mg/kg IP) followed by pimonidazole (PIM) IP and sacrificed at the indicated times. Serum ALT values were increased at 2, 4, 8, and 24 and 48 h compared to saline treated mice (*p<0.05).