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. Author manuscript; available in PMC: 2011 May 23.
Published in final edited form as: FASEB J. 2005 Mar;19(3):362–370. doi: 10.1096/fj.04-2364com

Figure 6.

Figure 6

TNF-α effects on atrogin1/MAFbx mRNA levels are dose dependent. C2C12 myotubes were exposed to TNF-α at the indicated concentrations for 2 h and total RNA was extracted for Northern blot analysis. Upper panel is a representative blot showing multiple atrogin1/MAFbx transcripts (left) and ethidium bromide-stained loading controls (right). Lower panel depicts averaged densitometry data from 3 separate experiments showing the dose dependence of atrogin1/MAFbx up-regulation; P < 0.03 by ANOVA.