Fig. 10.

Forced activation of p38 restores muscle regeneration in p55^−/−p75^−/− soleus. Adenovirus constructs encoding MKK6bE or GFP cDNA were injected into the hindlimb muscle of 3- to 4-day-old p55^−/−p75^−/− (KO) mice. At 6 wk of age, cardiotoxin was injected into the soleus of these mice as well as WT mice. Soleus was collected before (day 0) and 5 or 12 days after cardiotoxin injection. Paraffin-embedded sections were prepared and stained with hematoxylin and eosin.