FIGURE 7.
Comparison of tissue contents of monoamines and their metabolites in the cortex, nucleus accumbens, and striatum of Fut8+/+, Fut8+/−, and Fut8−/− mice. The turnover rates of monoamine neurotransmitters in the cortex, nucleus accumbens, and striatum of Fut8+/+, Fut8+/−, and Fut8−/− mice (3.5–4.5 months old) were assayed by HPLC as described under “Experimental Procedures.” Data are mean ± S.E.; n = 15. DOPAC, 3,4-dihydroxyphenylacetic acid; HVA, homovanillic acid; 5-HIAA, 5-hydroxyindolacetic acid.