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Kinetic constants
Ki values are means ± S.D. for n = 3 experiments.
| Inhibitor | Inhibition mechanism | Inhibition constant(s) |
|---|---|---|
| μm | ||
| FTY720 | Competitive | Kic = 2.0 ± 0.5 |
| (S)-FTY720 vinylphosphonate | Uncompetitive | Kiu = 14.5 ± 4.4 |
| SKi | Mixed | Kic = 17.0 ± 3.5; Kiu = 48.3 ± 11.5 |
