TABLE 1.

Dissociation constants and binding enthalpies of AdoMet, sinefungin, and AdoHcy to SET7/9

Ligand	KD	ΔH
	nm	kcal/mol
AdoMet	53 ± 3	−26.7 ± 0.1
Sinefungin	330 ± 24	−23.0 ± 0.2
AdoHcy	60,000 ± 5000	−24.4 ± 1.2