Table 3.
Multiple linear regression analyses of change in emphysema level (%LAA) and change in airway wall thickness (AWT-Pi10) by level fat-free mass index (FFMI) and level of fat mass index (FMI).
| Log(%LAA)* | AWT-Pi10** | |||||
|---|---|---|---|---|---|---|
| Beta | SE | P value | Beta | SE | P-value | |
| Subjects without COPD | ||||||
| FFMI | −0.04 | 0.02 | .528 | 0.16 | 0.01 | .002 |
| FMI | 0.09 | 0.01 | .053 | 0.22 | 0.01 | <.001 |
| Adjusted R2 | 0.26 | 0.33 | ||||
|
| ||||||
| Subjects with COPD | ||||||
| FFMI | −0.28 | 0.02 | .002 | 0.08 | 0.02 | .460 |
| FMI | 0.03 | 0.01 | .686 | 0.20 | 0.01 | .020 |
| Adjusted R2 | 0.48 | 0.30 | ||||
%LAA: percentage low attenuation areas less than −950 HU, AWT-Pi10: standardized airway wall thickness at an internal perimeter of 10 mm, FFMI: fat-free mass index, FMI: fat mass index.
*Adjusted for age, pack year, FEV1 (%pred), and AWT-Pi10,
**Adjusted for age, pack year, FEV1 (%pred), and %LAA.