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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Free Radic Biol Med. 2011 Mar 5;50(11):1536–1545. doi: 10.1016/j.freeradbiomed.2011.02.034

Fig 6. MS data obtained from the reaction of calf thymus DNA with CuCl2-H2O2 in the presence of DMPO.

Fig 6

Fig 6

(A) EIC of m/z 252.1 (unmodified 2′-deoxyadenosine) and of m/z 363.2 (DMPO-2′-deoxyadenosine) Panels 1 and 2 show the EIC obtained from the LC/MS of the control DNA (no DMPO present). Note the absence of the adduct ion. Panels 3 and 4 show the EIC's obtained from the DNA subjected to oxidation in the presence of DMPO. Note the presence of the adduct ion. Inset, shows the HPLC chromatogram, of the standard nucleosides and released nucleosides from the DNA digestion.(B) MS/MS of the ion of m/z 252.09 and m/z 363.16.