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. Author manuscript; available in PMC: 2011 May 23.
Published in final edited form as: Nat Neurosci. 2010 Jun 6;13(7):877–882. doi: 10.1038/nn.2569

Figure 3.

Figure 3

Gut hormones and melanocortin action in the CNS modulates hepatic HDL-C re-uptake pathways independent of food intake. (a–f) Changes in Scarb1 (a,d), Nr1h4 (FXR, b,e) and Nr2h5 (LRH-1, c,f) hepatic mRNA levels. Ghrelin (2.5 nmol d−1) or SHU9119 (24 nmol d−1) were icv infused for 7 d in pair-fed (pf) Wistar rats (mean ± s.e.m., n = 8, a–c). GLP-1 (2.5 nmol d−1) was icv infused for 48 h in C57BL/6 male mice (mean ± s.e.m., n = 6–8, d–f). *P < 0.05, **P < 0.01 and ***P < 0.001 versus saline (one-way ANOVA).