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Effect of the gut hormone ghrelin and melanocortin action in the CNS on the hepatic gene expression of components of cholesterol synthesis pathway. (a–d) Effect of 7-day icv infusion of ghrelin (2.5 nmol d−1) and SHU9119 (24 nmol d−1) on hepatic mRNA expression of Srebf2 (a), Hmgcr (b), Ldlr (c) and Lcat (d) in pair-fed Wistar rats. *P < 0.05 versus saline (one-way ANOVA, mean ± s.e.m., n = 8).
