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. Author manuscript; available in PMC: 2011 May 23.
Published in final edited form as: Mol Cell. 2008 Nov 7;32(3):359–370. doi: 10.1016/j.molcel.2008.10.015

Figure 7. Expression of Sin3 target genes after knock-down of Sin3.

Figure 7

(A) Gene expression analysis using quantitative real time RT-PCR of selected genes after ablation of Sin3. Myotubes were transfected 48 h after induction of differentiation and were isolated 96 after transfection. Expression levels of selected genes in Sin3 siRNA-transfected cells were compared to non-specific control (NS) transfected cells. The average of three independent experiments is shown. Error bars represent standard deviation. (B) Model detailing Sin3 function in differentiated muscle cells on a subset of E2F4 target genes. Me: methylation of H3K4 (green) and H3K27 (red); Ac: acetylation. See text for details.