Table 1.
Demographics and intraoperative characteristics of patients presenting for surgical repair of either a ventricular septal defect (VSD) or tetralogy of Fallot (ToF)
| Demographics and intraoperative profiles | ||
| Age (months) | 4.8±0.3 | |
| Weight (kg) | 5.6±0.2 | |
| Arterial oxygen saturation (%) | 96±1 | |
| Gender (M/F) | 18 / 19 | |
| Ethnicity (Caucasian / African American / Hispanic) | 21 / 15 / 1 | |
| Sample Size (n) | 37 | |
| Lesion type (n, %) | VSD | 17 (46%) |
| TOF | 20 (54%) | |
| Cross clamp time (min) | VSD | 56±5 |
| TOF | 86±3+ | |
| Cardiopulmonary bypass time (min) | VSD | 91±6 |
| TOF | 151±6+ | |
| Postoperative outcomes dichotomized by anti-fibrinolytic | ||
| WBC count at 4 hours (×103 / mL) | TXA | 10.9±0.7 |
| Aprotinin | 9.0±0.5* | |
| Maximum WBC count in the 48 hours perioperative period (×103 / mL) | TXA | 12.9±0.9 |
| Aprotinin | 13.2±0.7 | |
| Packed red blood cells (units) | TXA | 2 (1) |
| Aprotinin | 2 (1) | |
| Fresh frozen plasma (units) | TXA | 1 (1) |
| Aprotinin | 1 (1) | |
| Cryoprecipitate (units) | TXA | 0 (1) |
| Aprotinin | 0 (0) | |
| Platelets (units) | TXA | 1 (1) |
| Aprotinin | 1 (0) | |
| Sample size | TXA | 15 |
| Aprotinin | 22 | |
TXA: tranexamic acid
Continuous variables presented as Mean±SEM. Categorical variables presented as either number of subjects or median (interquartile range)
+
p<0.05 vs. VSD
*
p<0.05 vs. TXA.
t-test or ANOVA (as appropriate) used for continuous variables; χ2 test used for categorical variables