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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Pediatr Res. 2011 Apr;69(4):271–278. doi: 10.1203/PDR.0b013e31820efbcf

Figure 3. A1 adenosine receptor (A1AR) activation induces periventricular white matter injury.

Figure 3

Left panel: Neonatal rats reared in hypoxia manifest features of periventricular white matter injury including white matter loss and secondary ventriculomegaly (V). Reprinted from Ment LR et al. Brain Res Dev Brain Res 111:197–203; Copyright c 1998 Elsevier Science B.V., with permission. Right Panel: Neonatal rats treated with the A1 adenosine receptor (A1AR) agonist, N6-cylcopentyladenosine (CPA) manifest features of PWMI similar to that observed in hypoxia. Arrows depict location of ventricles.