Figure 4. Sprr2d expression is not altered in germ cell-deficient ovaries.

Expression of Sprr2d and Oct4 were examined by WISH in E12.5 XX +/+ and W^v/W^v germ cell-deficient gonads. Sprr2d was expressed at equal levels, and with a posterior bias, in +/+ (n = 4) (top, left panel) and W^v/W^v (n = 4) (top, right panel) gonads. As expected, the germ cell marker Oct4 was abundantly expressed in +/+ gonads (n = 4) (bottom, left panel), but was expressed in only a few cells in W^v/W^v gonads (n = 2) (bottom, right panel). A, anterior; P, posterior.