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. Author manuscript; available in PMC: 2011 May 23.
Published in final edited form as: Dev Dyn. 2009 Apr;238(4):812–825. doi: 10.1002/dvdy.21902

Figure 7. Sprr2d and 1700106J16Rik expression are decreased in Fog2, Sf1, and Wt1 mutant genital ridges.

Figure 7

Quantitative real-time RT-PCR was used to analyze Sprr2d and 1700106J16Rik (J16Rik) expression in E11.5 XX and XY genital ridges from fetuses with null mutations in Fog2 (A), Sf1 or Wt1 (B). Each bar represents the fold difference in expression compared to wildtype samples of the same sex. Error bars represent the standard error of mean. For all comparisons between −/− and +/+ samples, p < 0.05, except for J16Rik expression in XY Wt1−/− vs. Wt1+/+ (p = 0.06) and XY Fog2−/− vs. Fog2+/+ (p = 0.08). However, all data follows a similar trend. Sample numbers are: Fog2 (XX +/+ [6], +/− [6], −/− [6]; XY +/+ [3], +/−[6], −/− [5]), Sf1 (XX +/+ [4], +/− [6], −/− [2]; XY +/+ [9], +/− [5], −/− [4]), Wt1 (XX +/+ [4], +/−[≥6], −/− [3]; XY +/+ [9], +/− [5], −/− [≥2]). Because the Sf1 and Wt1 knockout alleles are both on the B6 background, data from +/+ gonads of each sex were pooled for comparisons.