Table 3.
Non-analytical specifications of PoCT creatinine devices available in Australia and New Zealand (as noted in Table 1).
| Device | i-STAT | ABL 800 Flex | Reflotron | Dri-Chem 4000 | StatSensor | Piccolo |
|---|---|---|---|---|---|---|
| Manufacturer | Abbott POC | Radiometer | Roche | Fuji Film | Nova Biomedical | Abaxis |
| Method Principle | Enzymatic with amp biosensor | Enzymatic with amp biosensor | Enzymatic with dye reflectance | Enzymatic with dye absorbance | Enzymatic with amp biosensor | Enzymatic with indicator absorbance |
| Calibration Traceable To | SRM 967 | IDMS via HPLC | Not available | SRM 914 | Not available | SRM 967 |
| Consumable | Cartridge | Sensor Cassette | Dry strip | Dry slide | Dry strip | Rotor |
| Sample Type | Whole blood (A,V,C) | Whole blood (A,V,C) or serum, plasma | Whole blood (V,C) or serum, plasma | Serum or plasma | Whole blood (A,V,C) | Whole blood, serum or plasma |
| Sample Volume | 65 μL | 125 (c)/250 (syr) μL | 30 μL | 10 μL | 1 μL | 9 μL |
| Time for Result | 2 min | 1 min | 2 min | 5 min | 0.5 min | 8.5 min, then 0.6 min |
| Measuring Range | 18–1768 μM | 10–2000 μM | 45–884 μM | 18–2122 μM | 27–1056 μM | 18–1768 μM |
| eGFR Calculation | No | Yes | Yes | No | Yes | No |
| Size, Weight | Hand held, 0.7 kg | Benchtop, 33 kg | Benchtop, 5 kg | Benchtop, 20 kg | Hand held, 0.4 kg | Benchtop, 5 kg |
| Power | AC or battery | AC | AC | AC | AC or battery | AC |
| Connectivity | Yes | Yes | Yes | Yes | Yes | Yes |
| Other Analytes | Elu, Bgas, metabs, Hb, coag, cardiac | Elu, Bgas, metabs | Elu, Hb, metabs, lipids, enzymes | Elu, Hb, metabs, lipids, enzymes | Nil | Elu, metabs, lipids, enzymes |
SRM = Standard Reference Material; IDMS = Isotope Dilution Mass Spectrometry; amp, amperometric; A = arterial, V = venous, C = capillary; c =capillary, syr = syringe; AC = mains power; Elu = electrolytes, Bgas = blood gases, coag = coagulation, metabs = metabolites, Hb = haemoglobin.