Table 1. rab11-null FSCs have a wildtype or near wildtype half-life.
% marked germaria at different days ACI (total number of germaria counted) | ||||
genotype of marked clones | 11 | 16 | 24 | Half-life |
FRT5377, rab11-null | 18.1 (204) | 14.8 (203) | 11.2 (155) | 17.2–19.0 days* |
FRT5377, rab11+ | 18.7 (315) | 15.7 (191) | 12.1 (298) | 19.8–21.2 days* |
*half-lives were calculated for each of the two intervals 11–16 days and 16–24 days using the equation half-life = elapsed time (days)×log 2/log [initial percentage/end percentage], which assumes that FSC loss occurs randomly, and thus linearly over time.