Table 1. Details of CNEs tested in transgenic mice.
CNE construct | Length of CNE(s) (bp) | Percentage identity of CNE(s) | Distance from TSS of human LHX2 | Location of CNE(s) |
CNE1 | 76 | 69.1% | 619 kb | DENND1A intron 20 |
CNE2/3 | 210 | 75.0% | 516 kb | DENND1A intron 13 |
CNE4 | 119 | 71.4% | 324 kb | DENND1A intron 5 |
CNE5/6 | 380 | 72.3% | 269 kb | DENND1A intron 5 |
CNE7 | 51 | 64.7% | 242 kb | DENND1A intron 3 |
CNE8 | 120 | 67.7% | 234 kb | DENND1A intron 3 |
CNE9 | 53 | 69.8% | 222 kb | DENND1A intron 3 |
CNE10 | 145 | 89.7% | 219 kb | DENND1A intron 2 |
TSS: transcription start site.