Table 3. ApoE allele and genotype frequencies in PPA, PRAD and NC.
APOE genotype | Allele frequency | ||||||||
---|---|---|---|---|---|---|---|---|---|
ε2/ε2 | ε2/ε3 | ε2/ε4 | ε3/ε3 | ε3/ε4 | ε4/ε4 | ε2 | ε3 | ε4 | |
PPA | |||||||||
All n=149 | 1 (0.7) | 11 (7.4) | 2 (1.3) | 95 (63.8) | 36 (24.2) | 4 (2.7) | 15 (5.0) | 237 (79.5) | 46 (15.4) |
Male n=72 | 0 (0) | 7 (9.7) | 0 (0) | 43 (44.3) | 20 (27.8) | 2 (2.6) | 7 (4.9) | 113 (78.5) | 24 (16.7) |
Female n=77 | 1 (1.3) | 4 (5.2) | 2 (2.6) | 52 (67.5) | 16 (20.8) | 2 (2.8) | 8 (5.2) | 124 (80.5) | 22 (14.3) |
PRAD | |||||||||
All n=179 | 0 (0) | 7 (3.9) | 4 (2.2) | 56 (31.3) | 87 (48.6) | 25 (14.0) | 11 (3.1) | 206 (57.5) | 141 (39.5) |
Male n=59 | 0 (0) | 1 (1.7) | 1 (1.7) | 21 (35.6) | 29 (49.2) | 7 (11.9) | 2 (1.7) | 72 (61.0) | 44 (37.3) |
Female n=120 | 0 (0) | 6 (5.0) | 3 (2.5) | 35 (29.2) | 58 (48.3) | 18 (15.0) | 9 (3.7) | 134 (55.8) | 97 (40.4) |
NC | |||||||||
All n=330 | 1 (0.3) | 33 (10.0) | 8 (2.4) | 207 (62.7) | 75 (22.7) | 6 (1.8) | 43 (6.5) | 522 (79.1) | 95 (14.4) |
Male n=81 | 0 (0) | 6 (7.4) | 2 (2.5) | 54 (66.7) | 17 (21.0) | 2 (2.5) | 8 (4.9) | 131 (80.9) | 23 (14.2) |
Female n=249 | 1 (0.4) | 27 (10.8) | 6 (2.4) | 153 (61.5) | 58 (23.3) | 4 (1.6) | 35 (7.0) | 391 (78.5) | 72 (14.5) |
The numbers in ( ) represent the % of each allele or genotype.