Table 2.
SIPS Scores by Diagnostic Group
Significant group contrasts are noted, as are the effect sizes for contrasts between the two high-risk groups.
| Controls | SPD | 22q11.2DS | SPD v. 22q11.2DS | ||||
|---|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | Mean | SD | Cohen’s d | |
| POSITIVE SYMPTOMS ‡† | 0.652 | 0.616 | 2.070 | 1.193 | 1.446 | 0.577 | 0.666 |
| unusual thought content/delusional ideas ‡† | 0.652 | 0.982 | 2.435 | 1.879 | 1.478 | 0.665 | 0.679 |
| suspiciousness/persecutory ideas ‡† | 0.652 | 1.027 | 2.348 | 1.695 | 1.652 | 1.152 | 0.480 |
| grandiosity | 0.739 | 0.915 | 1.304 | 1.428 | 0.739 | 1.096 | 0.444 |
| perceptual abnormalities/hallucinations ‡† | 0.696 | 0.926 | 2.435 | 1.830 | 1.783 | 1.204 | 0.421 |
| disorganized communication † | 0.609 | 0.891 | 2.000 | 1.537 | 1.478 | 1.123 | 0.388 |
| NEGATIVE SYMPTOMS ‡† | 0.574 | 0.735 | 1.808 | 1.352 | 2.058 | 0.830 | −0.223 |
| social anhedonia ‡† | 0.826 | 1.370 | 2.826 | 2.059 | 3.000 | 1.651 | −0.093 |
| avolition ‡ | 0.609 | 1.340 | 1.913 | 1.730 | 1.957 | 1.522 | −0.027 |
| reduced expression of emotion | 0.826 | 1.114 | 1.696 | 1.941 | 1.696 | 1.550 | 0.000 |
| decreased experience of emotion/self | 0.391 | 0.722 | 1.000 | 1.537 | 1.043 | 1.186 | −0.031 |
| decreased ideational richness ‡† * | 0.130 | 0.344 | 1.348 | 1.229 | 2.913 | 1.676 | −1.065 |
| deterioration of role functioning ‡ | 0.609 | 1.373 | 1.826 | 1.946 | 1.913 | 1.443 | −0.0508 |
| DISORGANIZED SYMPTOMS ‡† | 0.326 | 0.449 | 1.630 | 0.935 | 1.576 | 1.001 | 0.056 |
| odd behavior/appearance ‡† | 0.130 | 0.344 | 1.696 | 1.608 | 1.435 | 1.273 | 0.180 |
| bizarre thinking † | 0.174 | 0.650 | 1.174 | 1.193 | 0.783 | 1.043 | 0.349 |
| trouble with focus/attention ‡† | 0.826 | 1.267 | 2.304 | 1.396 | 2.652 | 0.935 | −0.2929 |
| problems with hygiene ‡† | 0.174 | 0.491 | 1.391 | 1.500 | 1.304 | 1.608 | 0.056 |
| GENERAL SYMPTOMS ‡† | 0.467 | 0.524 | 1.859 | 1.290 | 1.826 | 0.831 | 0.030 |
| sleep disturbance | 1.043 | 1.331 | 2.391 | 1.751 | 1.609 | 1.406 | 0.493 |
| dysphoric mood ‡† | 0.565 | 0.896 | 2.696 | 2.204 | 2.391 | 1.500 | 0.162 |
| motor disturbance ‡ | 0.087 | 0.417 | 0.696 | 1.490 | 1.826 | 1.557 | −0.742 |
| impaired tolerance to stress ‡ | 0.174 | 0.388 | 1.696 | 2.077 | 1.478 | 1.201 | 0.129 |
*
Significant difference between Schizotypal Personality Disorder (SPD) and 22q11.2 Deletion Syndrome (22q11.2DS) groups at p <.01
†
Significant difference between control and SPD groups at p <.01
‡
Significant difference between control and 22q11.2DS groups at p <.01