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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: J Clin Epidemiol. 2011 Jan 5;64(7):749–759. doi: 10.1016/j.jclinepi.2010.10.004

Table 2.

Conditions Included in the Romano Implementation of the Charlson Index and the Elixhauser Comorbidity Classification System and Corresponding Weights Derived by Schneeweiss et al and van Walraven et al and New Weights Derived for Combined Score in the Development Cohort (PA/PACE) in the Baseline Year

Condition Prevalence in development cohort (PA/PACE, 2004), % Medicare weights for Charlson/Romano score (based on data from 1995) van Walraven weights for Elixhauser score (based on data from 1996–2008) Association with 1-year mortality, odds ratio* (based on data from 2005) 95% Confidence interval New weights for combined score
Myocardial infarcta 7.9 1 1.12 1.05, 1.19 0
Congestive heart failureb 23.3 2 7 1.75 1.67, 1.84 2
Peripheral vascular disorderc 32.7 1 2 1.29 1.24, 1.35 1
Cerebrovascular diseasea 21.3 1 1.04 0.99, 1.09 0
Dementiaa 9.0 3 1.80 1.69, 1.91 2
Chronic pulmonary diseaseb 25.7 2 3 1.48 1.42, 1.55 1
Rheumatoid arthritis/collagen vascular diseasesc 11.4 0 0 0.91 0.85, 0.97 0
Ulcer diseasea 2.8 0 0 0.90 0.80, 1.00 0
Mild liver diseased 2
Uncomplicated diabetesc 23.5 1 0 1.16 1.10, 1.22 0
Hemiplegiaa 1.5 1 1.27 0.71, 2.28 1
Renal failurec 6.9 3 5 1.61 1.51, 1.72 2
Complicated diabetesc 10.6 2 0 1.23 1.15, 1.32 1
Any tumora 11.6 2 4 1.26 1.19, 1.34 1
Leukemiae
Lymphomae 9
Moderate or severe liver diseased 4
Metastatic cancerb 1.8 6 12 5.17 4.66, 5.73 5
HIV/AIDSb 0.0 4 0 0.84 0.17, 4.08 −1
Cardiac arrhythmiasc 25.2 5 1.25 1.19, 1.31 1
Valvular diseasec 18.9 −1 1.03 0.98, 1.09 0
Pulmonary circulation disordersc 3.2 4 1.40 1.28, 1.53 1
Hypertensionc 82.3 0 0.72 0.68, 0.76 −1
Paralysisc 1.5 7 1.03 0.57, 1.86 0
Hypothyroidismc 25.3 0 0.96 0.91, 1.01 0
Coagulopathyc 5.2 3 1.24 1.15, 1.34 1
Obesityc 0.1 −4 0.94 0.35, 2.48 0
Weight lossc 1.5 6 1.81 1.62, 2.03 2
Fluid and electrolyte disordersc 16.2 5 1.35 1.28, 1.42 1
Blood loss anemiac 2.6 −2 1.10 0.99, 1.22 0
Deficiency anemiasc 27.4 −2 1.25 1.19, 1.31 1
Alcohol abusec 0.4 0 1.48 1.10, 1.98 1
Drug abusec 0.2 −7 0.86 0.58, 1.29 0
Psychosisc 7.3 0 1.24 1.16, 1.33 1
Depressionc 11.9 −3 1.08 1.02, 1.15 0
Neurodegenerative disordersc 5.2 6 1.15 1.06, 1.25 0
Liver diseasec 1.2 11 1.32 1.11, 1.57 1
*

In addition to each of the conditions, the model was adjusted for age and sex

a

Romano definition used rather than Elixhauser definition

b

Elixhauser and Romano definitions are the same

c

Elixhauser definition used rather than Romano definition

d

Included in definition of ‘Liver disease’

e

Included in definition of ‘Any tumor’