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. Author manuscript; available in PMC: 2012 May 24.
Published in final edited form as: Curr Biol. 2011 May 5;21(10):825–834. doi: 10.1016/j.cub.2011.04.010

Figure 1.

Figure 1

C. elegans DOS-motif proteins are required for response to octanol. (A) Octanol responses of animals carrying the likely null alleles osm-11(rt142), osm-7(tm2256), dos-1(ok2398), and partial loss of function allele dos-2(tm4515). *p<0.0005 vs. wild type (WT). (B) osm-11 function is not required during development for octanol response in adults. $p<10−4 vs. control (RNAi). *p>0.05 vs. wild type, #p>0.05 vs. osm-11(null);osm-11(OE) no HS. (C) OSM-11 protein accumulates in coelomocytes. osm-11p::gfp reporter constructs do not drive GFP expression in coelomocytes [4]. Top left: Representative image of OSM-11 accumulation in a coelomocyte using αOSM-11 antisera [4]. Bottom left: Osmotic stress likely results in diminished OSM-11 secretion by seam cells into pseudocoelom. Top and bottom right: GFP expression (unc-122p:: gfp) in coelomocytes [53]. Scale bar=6 μm. See Supplemental Methods 1 for details.