Skip to main content
. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Exp Neurol. 2011 Feb 22;229(2):288–299. doi: 10.1016/j.expneurol.2011.02.012

Table 1.

Effects of unilateral medial forebrain bundle (MFB) 6-OHDA or sham lesion on concentrations of striatal DOPAC and DA.

Intact vs. lesioned DOPAC (ng/mg) DA (ng/mg)
Subset 6-OHDA-lesioned (n=7)
   Intact (right) 3.42 (± 0.16) 11.34 (± 1.44)
   Lesioned (left) 0.06 (± 0.01)*+ 0.03 (± 0.01)*+
   (Lesioned/intact %) 1.70% 0.30%
Subset sham-lesioned (n=7)
   Intact (right) 4.09 (± 0.74) 10.30 (± 1.49)
   Lesioned (left) 3.41 (± 0.79) 8.74 (± 1.53)
   (Lesioned/intact %) 88.45% 92.22%

Values are nanogram DOPAC or DA per milligram protein and percentage of intact striata. Differences between group means were determined by two-way ANOVAs and planned comparison analyses.

*

p<0.05 compared to intact sides;

+

p<0.05 compared to lesioned side (sham)