Table 1.
Analytical characteristics of the chitosan modified microsensor and comparison with the literature data.
| Detection Method |
Diameter Size (µm) |
Linear Range (mol/L) |
Sensitivity/ | LOD (nM) |
Rejection of interferences |
Ref. | |
|---|---|---|---|---|---|---|---|
| DNA-PPyox/CFME | DPV | 6 | 1×10−8 – 1×10−6 | - | 7 | AA up to 2×10−2M | [20] |
| BDD-Pt | DPV | 40 | 2×10−6 – 10 ×10−6 | 19.4 pA/µM | 1050 | - | [19] |
| CFME | DPV | 30 | 7.2 pA/µM | 3080 | - | [19] | |
| Poly[Ni(TSPc)]/Nafion/CFME | SWV | 8 | 5×10−9 – 9×10−8 | 36 nA/µM | 3.8 | 5-HIAA up to 31 mg/L DOPAC up to 11 mg/L Rejects AA | [23] |
| GNP/LC/GCE | SWV | 3000 | 6×10−8 – 6×10−6 | - | 20 | AA up to 6×10−4M | [24] |
| BDD-Si | Amperometry / Flow injection | Geometric area of 0.64 cm2 | 1×10−8 – 5×10−5 | 25 nA/µM | 20 | - | [25] |
| CNTs/Nafion/CFME | DPV | 30 | 5×10−9 – 2×10−7 | 83.65 nA/µM | 1 | - | [3] |
| Chit/CFME | DPV |
5 Geometric area of 0.079 mm2 |
2×10−9 – 1×10−7 | 5.1243 nA/µM | 1.6 | AA up to 5×10−4M | This work |
PPyox: overoxidized polypyrrole; BDD: boron doped diamond; Poly[Ni(TSPc)]: polymeric tetrasulfonated phtalocyanines; GNP: gold nanoparticles; LC: L-cysteine; AA: ascorbic acid; DOPAC: 3,4-dihydroxyphenylaceticacid; 5-HIAA: 5-Hydroxyindole-3-acetic acid, GCE: glassy carbon electrode; CNTs: carbon nanotubes; SWV: square wave voltammetry; DPV: differential pulse voltammetry.