Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Overview of the complement cascade. Activation of all three complement pathways results in cleavage of C3, leading to formation of C3a and C5a and ultimately membrane attack complex. Decay accelerating factor (DAF), CD46 and CD59 are complement regulatory molecules.
